Dr. Paula A. Mazzer

Assistant Professor

Education:

Ph.D. in Chemistry, Kent State University, 2002
B.A. in Biology, University of Delaware, 1991

Research Interests:

The Mazzer lab is investigating the health effects of complex environmental mixtures. The current project is the potential health effects of airborne particulate matter (PM)-primarily the organic fraction-using a molecular pathology approach. Determining the underlying toxicologic mechanisms by which air pollutant particles induce adverse health effects has been identified as a key scientific priority by the National Academy of Sciences.

The field of toxicology is being transformed by modern bioanalytical and molecular biological techniques into one that focuses on molecular-level analysis-an approach termed "molecular pathology." My group uses a multifaceted approach which combines molecular level bioanalytical assays-such as tetramethylammonium hydroxide (TMAH) thermochemolysis and DNA oxidation product or adduct identification-with cellular metabonomic analysis via liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS).

Location:

Office: Alfriend Chemistry Building Room 401
Laboratory Alfriend Chemistry Building Rooms 205 and 209

Contact Information:

Dr. Paula Mazzer
Department of Chemistry and Biochemistry
Old Dominion University
4541 Hampton Blvd.
Norfolk, VA 23529-0126

Office Phone: 757-683-4089
Laboratory Phone: 757-683-4086
Fax number: 757-683-4628

e-mail: pmazzer@odu.edu