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Mass Spectrometry

NMR

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Instruments

Bruker Apex-Qe

A Hybrid Qh-FTICR-MS with an extended high performance actively shielded 12 Tesla magnet

 

Capabilities:

  • Exact mass to sub ppm levels
  • High resolution capability for direct analysis of complex mixtures (600,000 FWHM)
  • Simultaneous detection of ions in a wide m/z range
  • LC/MS/MS with data dependent acquisition
  • Exact mass for MS(n)
  • Qh front end provides sensitive, selective ion enrichment and with Bruker Biotools software provides top down de Novo protein sequencing and discovery of Post Translational Modifications.
  • CID, ECD, and IRMPD (Infrared Multiphoton Dissociation) capabilities offer three different fragmentation options for obtaining structural information

Ion Sources:

  • Apollo-II Ion Funnel with electrospray and nanospray provides both positive ion and negative ion capabilities for polar compounds
  • APPI (Atmospheric Pressure Photoionization) source provides ionization capabilities for non polar compounds